Screening patients with metastatic breast cancer for psychiatric disease: a cross sectional study

• DOI: 10.12688/f1000research.79400.1
• Publication Date: 2022-01-21T14:30:28Z
• Authors: Raquel Basto; Cecília Caramujo; Inês Ferreira Gomes; Teresa Fraga; Joana Correia Mag...; Maria João Sousa; Sabrina de Jesus; Ana Raquel Monteiro; Adriana Pestana-S...; Teresa Carvalho; Emília Albuquerque; Gabriela Sousa
• Keywords: Cross-sectional study; Open peer review; Psychiatric Disease

<ns7:p><ns7:bold>Background: </ns7:bold>Cancer patients are at risk of developing some level psychological dysregulation, depending on a series variables related to the tumor, environment, and patient. In this context, it becomes important define difference between psychiatric disorder study its prevalence. The primary endpoint is evaluate prevalence disorders in sample Portuguese with metastatic breast cancer assess relationship these characteristics oncological disease.</ns7:p><ns7:p> <ns7:bold>Methods: </ns7:bold>Cross-sectional, single-center female diagnosed carcinoma under palliative treatment November 2020 May 2021. Psychiatric were screened by applying filling-out MMSE, HADS, BSI, WHOQoL-Bref instruments outpatient daycare unit when present for treatmen.</ns7:p><ns7:p> <ns7:bold>Results: </ns7:bold>A total<ns7:bold> </ns7:bold>of 91 included, median age 59.79 years<ns7:bold>.</ns7:bold> None had cognitive impairment (MMSE). HADS scale: 18.7% scored anxiety 17.6% depression. subscale score &gt; 8 (HADS) was ovarian function suppression (p&lt;0.001), neoadjuvant therapy type second-line (p=0.024). depression &gt;8 surgery performed (p= 0.022), molecular subtype tumor (p=0.020), occurrence grade 3-4 toxicities first (p=0.018), third-line treatments (p=0.031).</ns7:p><ns7:p> <ns7:bold>Conclusion: </ns7:bold>The screening through application scales medical oncology team may be able aid diagnosis potentially lead referral intervention an earlier stage.</ns7:p>