Evaluation of Radioprotective Effects of Rajgira (Amaranthus paniculatus) Extract in Swiss Albino Mice

• DOI: 10.1269/jrr.46.233
• Publication Date: 2005-06-28T09:48:22Z
• Authors: Anita Krishna; Ashok Kumar
• Keywords: Aqueous extract; Parenchyma

The radioprotective efficacy of aqueous extract Rajgira (Amaranthus paniculatus) leaves against whole body gamma radiation was studied in Swiss albino mice. oral administration at 800 mg/kg weight/day for 15 consecutive days before exposure to found be effective with the LD50/30 values 6.33 and 8.62 Gy irradiation alone Rajgira+irradiation group, respectively, giving a dose reduction factor 1.36. This effect accompanied increased endogenous spleen colonies weight without any side or toxicity, as well modulation radiation-induced decrease reduced glutathione increase lipid peroxidation assessed liver blood.