Prenatal, early-life, and childhood exposure to source-specific air pollution and behavioural problems in the ALSPAC cohort

• DOI: 10.1289/isee.2022.p-1014
• Publication Date: 2023-01-17T18:15:37Z
• Authors: Yingxin Chen; Yutong Cai; John Gulliver; Charlotte Clark; Anna Hansell
• Keywords: Prosocial Behavior; Longitudinal Study

Background and Aim: Particulate matter ≤10 μm in aerodynamic diameter (PM10) exposure may influence brain development be related to emotional behavioural problems children. This study aims investigate at ages 9 16 years relation PM10 exposures during pregnancy, infancy, childhood the Avon Longitudinal Study of Parents Children (ALSPAC). Methods: We assessed individual modelled (PM10_total) as well specifically from road traffic (PM10_road) 0–6 months, 7–12 up age years. used parent-completed Strengths Difficulties Questionnaire (SDQ) assess (N=5,209) (N=3,609) Associations between behaviour were examined using linear regression models, adjusted for individual-level confounders. Results: found adverse associations with but not Exposure PM10_total whole pregnancy period was positively associated higher total difficulties score (0.049; 95% confidence interval [CI], 0.004 0.095) per 1 μg/m3 higher, suggesting more frequent problems. did find clear evidence a sensitive PM10_road. At years, lower prosocial scores (-0.115; CI, -0.185 -0.044), indicating less developed behaviour, similar seen 0–8 also PM10_road conduct . Conclusion: early 1990s increased children ALSPAC cohort. Keywords: Air pollution; problems;