Complex approach to skin repair in an extensively burned child: a case study

• DOI: 10.12968/jowc.2020.29.8.458
• Publication Date: 2020-08-17T14:51:09Z
• Authors: Robert Zajicek; Richard Kubok; Nikola Petrova; Monika Tokarik; Eva Matouskova; Peter Gal
• Keywords: Skin grafting; Acellular Dermis; Artificial skin

The limited amount of donor sites and loss dermis are major challenges in the therapy extensively burned patients. Here, we present a complex treatment approach an eight-year-old boy with full-thickness burns on 90% total body surface area, using simple efficient techniques tissue engineering. To obtain sufficient skin for grafting repeatedly harvested same anatomical areas. Acceleration site healing was achieved by suspension noncultured autologous cells (NASC) acellular porcine (Xe-Derma (XD), Czech Republic). Moreover, such wound management allowed up to six reharvestings, compared one-to-three procedures following routine treatment. Bilayer Integra template (Integra LifeSciences Corp., US) used as dermal substitute over 60% burns. Following successful vascularisation neodermis 3–4 weeks, templates were covered meshed split-thickness grafts (STSG), or Meek autografts, facilitated NASC/XD. We may conclude that ‘sandwich’ technique approach, combining four biological covers (Integra, STSG, NASC XD), significantly contributed repair patient.