[Outcome of otolith organ function after treatment of sudden sensorineural hearing loss].

• DOI: 10.13201/j.issn.2096-7993.2020.11.008
• Publication Date: 2020-11-01
• Authors: Juan Hu; Zichen Chen; Yuzhong Zhang; Xinyu Wei; Huandi Zhao; Pengyu Ren; Peng Han; Ying Cheng; Wendi Shi; Qing Zhang
• Keywords: Pure tone audiometry

Objective:This study aimed to assess the clinical practice value of ocular vestibular evoked myogenic potential（oVEMP） and cervical potential（cVEMP） in monitoring rehabilitation function patients with suddensen sorineural hearing loss（SSHL）. Method:Twenty-four SSHL were retrospectively enrolled， showing no VEMP response on affected side but exhibiting responses after therapies We analyzed improvement restoration parameters response. Result:After treatment, seven showed recovery, including three cases both oVEMP cVEMP one case recovery. Between recoved group unrecoved group, before significant difference was found thresholds pure-tone audiometry（PTA）. However, exhibited lower PTA better shift （P<0.01）. Multivariate analysis revealed that recovery independent risk factor for therapeutic effect SSHL. Conclusion:The Combination is an objective tool assessing otolithic end organ during dynamic functional could predict auditory improvement.目的：探讨突发性聋（突聋）治疗后耳石器功能转归情况，以明确突聋患者治疗后内耳病损的恢复情况及预后判断指标。 方法：随访24例突聋患者的听力及眼肌前庭诱发肌源性电位（oVEMP）和颈肌前庭诱发肌源性电位（cVEMP）恢复情况。 结果：24例患者，治疗前oVEMP无反应5例，cVEMP无反应8例，oVEMP及cVEMP均无反应11例。治疗后共7例患者表现出oVEMP和/或cVEMP波形恢复，其中3例oVEMP恢复反应，1例cVEMP恢复反应，3例oVEMP及cVEMP均恢复反应。根据治疗后VEMP是否恢复分为恢复组和未恢复组，两组间治疗后听力水平及听力改善程度的差异均有统计学意义（P<0.01）。多元Logistic回归分析显示，VEMP恢复是影响突聋预后的独立危险因素。 结论：VEMP能够检测部分突聋患者的耳石器功能损伤并动态监测其转归，VEMP恢复是影响突聋预后的独立危险因素，对判断预后及确定治疗周期具有重要意义。.