Randomized Trial of Physical Activity and Calcium Supplementation on Bone Mineral Content in 3- to 5-Year-Old Children

• DOI: 10.1359/jbmr.2003.18.5.885
• Publication Date: 2006-04-26T22:59:46Z
• Authors: Bonny Specker; Teresa Binkley
• Keywords: Gross motor skill; Bone mineral content

Abstract A meta-analysis of adult exercise studies and an infant activity trial show a possible interaction between physical calcium intake on bone. This randomized supplementation was conducted in 239 children aged 3-5 years (178 completed). Children were to participate either gross motor or fine activities for 30 minutes/day, 5 days per week 12 months. Within each group, received (1000 mg/day) placebo. Total body regional bone mineral content by DXA 20% distal tibia measurements peripheral quantitative computed tomography (pQCT) obtained at 0 Three-day diet records 48-h accelerometer readings 0, 6, Higher levels observed versus groups, greater placebo (1354 ± 301 vs. 940 258 mg/day, p < 0.001). Main effects group not significant total leg DXA. However, the difference gain more pronounced receiving (interaction, = 0.05). had periosteal endosteal circumferences pQCT compared with study completion (p There (both ≤ 0.02) supplement groups both cortical thickness area: among placebo, area smaller activity, but calcium, larger activity. These findings indicate that modifies response young children.