The progress of tissue resident memory T-cells against tumors

• DOI: 10.1360/ssv-2020-0024
• Publication Date: 2020-11-13T03:27:07Z
• Authors: QiongLi WU; ShuangPeng KANG; ChangYou WU

<p indent="0mm">Most effector T cells are known to die as only a few of them became memory following immune responses. According their distribution, function, and transcription factors, can be divided into cells, central tissue resident (T_RM). The do not circulate in the blood lymph nodes but found non-lymphoid tissues, which includes skin mucous membranes, urogenital system, brain, respiratory lung, liver tissues. form play defense response directly quickly when pathogens invade In addition, also very important role responses tumors, allergic, autoimmune diseases. include CD4⁺ CD8⁺ that express cell surface molecules CD69 and/or CD103 produce cytokines killing functions during well linking original adaptive immunity initiate systemic response. studies have shown function is controlled by regulatory (Treg) this paper, differentiation tumors reviewed.