Non-contact all-optic OCT–PAM imaging with shared detection light

• DOI: 10.1364/ao.555161
• Publication Date: 2025-03-31T14:03:32Z
• Authors: Ning Ding; Ben Xiang; Huiwen Jiang; Jinyun Yue; Yao Yu; Jian Liu; Yuqian Zhao; Jingmin Luan; Yanqiu Yang; Yi Wang; Zhenhe Ma

We proposed a non-contact all-optic OCT–PAM dual-modal system based on a single detection light source. A homodyne low-coherence interferometer was adopted to detect the vibration induced by photoacoustic excitation. The optical coherence tomography (OCT) and photoacoustic microscopy (PAM) shared the same broadband light source for signal detection, thus simplifying the dual-modal system and making it compact. Using the proposed system, we performed absorption-scattering imaging of human hairs, measured the femoral artery and vein flow rates in mice, and imaged the auricle blood vessels in mice in vivo. The combination of OCT and PAM can provide complementary biological tissue information and offer a richer reference for the diagnosis of diseases.