Hollow optical-fiber based infrared spectroscopy for measurement of blood glucose level by using multi-reflection prism

• DOI: 10.1364/boe.7.000701
• Publication Date: 2016-01-29T15:56:47Z
• Authors: Saiko Kino; Suguru Omori; Takashi Katagiri; Yuji Matsuura
• Keywords: Prism; Reflection; Attenuated total reflection

A mid-infrared attenuated total reflection (ATR) spectroscopy system employing hollow optical fibers and a trapezoidal multi-reflection ATR prism has been developed to measure blood glucose levels. Using brought about higher sensitivity, the flat wide contact surface of resulted in measurement reproducibility. An analysis vivo measurements human inner lip mucosa revealed clear signatures difference spectra between ones taken during fasting state after ingestion solutions. calibration plot based on absorption peak at 1155 cm(-1) that originates from pyranose ring structure gave errors less than 20%.