Spatial wavefront shaping with a multipolar-resonant metasurface for structured illumination microscopy [Invited]

• DOI: 10.1364/ome.520736
• Publication Date: 2024-03-28T12:00:08Z
• Authors: Tamal Roy; Peter T. Brown; Douglas P. Shepherd; Lisa V. Poulikakos
• Keywords: Spatial light modulator

Structured illumination microscopy (SIM) achieves superresolution in fluorescence imaging through patterned and computational image reconstruction, yet current methods require bulky, costly modulation optics high-precision optical alignment, thus hindering the widespread implementation of SIM. To address this challenge, work demonstrates how nano-optical metasurfaces, rationally designed to tailor far-field wavefront at sub-wavelength dimensions, hold great potential as ultrathin, single-surface, all-optical modulators for We computationally demonstrate principle with a multipolar-resonant metasurface composed silicon nanostructures that generate versatile wavefronts far field upon variation polarization or angle incident light. Algorithmic optimization is performed identify seven most suitable patterns SIM generated by based on three key criteria. quantitatively (mrm-SIM) resolution gain comparable conventional applying optimal metasurface-generated simulated fluorescent objects reconstructing using proximal gradient descent. Notably, we show mrm-SIM these gains pattern circumvents complex equipment alignment requirements methodologies. The presented here paves way metasurface-enabled experimental simplification structured microscopy.