Genetic Control of Organ Shape and Tissue Polarity

• DOI: 10.1371/journal.pbio.1000537
• Publication Date: 2010-11-09T20:34:01Z
• Authors: Amelia A. Green; J. Richard Kennaway; Andrew I. Hanna; J. Andrew Bangham; Enrico Coen
• Keywords: Polarity (international relations); Antirrhinum; Cell polarity

The mechanisms by which genes control organ shape are poorly understood. In principle, may modifying local rates and/or orientations of deformation. Distinguishing between these possibilities has been difficult because interactions patterns, orientations, and mechanical constraints during growth. Here we show how a combination growth analysis, molecular genetics, modelling can be used to dissect the factors contributing shape. Using Snapdragon (Antirrhinum) flower as an example, development reflects tissue that vary spatially temporally form dynamic field. This field is under several dorsoventral influence action modelled assuming they modulate specified parallel or perpendicular established few key organisers polarity. Models in only do not fully account for observed fields shapes. However, data readily explained model also modify particular, genetic polarity at ventral petal junctions distal boundaries allows both accounted wild type mutants. results suggest played role evolution