Seroprevalence of SARS-CoV-2 and risk factors in Bantul Regency in March-April 2021, Yogyakarta, Indonesia

• DOI: 10.1371/journal.pgph.0000698
• Publication Date: 2023-06-26T17:20:52Z
• Authors: Riris Andono Ahmad; Citra Indriani; Risalia Reni Aris...; Ratih Oktri Nanda; Yodi Mahendradhata; Tri Wibawa
• Keywords: Seroprevalence

COVID-19 case counts in Indonesia inevitably underestimate the true cumulative incidence of infection due to limited diagnostic test availability, barriers testing accessibility and asymptomatic infections. Therefore, community-based serological data is essential for understanding prevalence This study aims estimate seroprevalence SARS-CoV-2 factors related seropositivity Bantul Regency, Yogyakarta, Indonesia. A cross-sectional involving 425 individuals 40 clusters was conducted between March April 2021. Participants were interviewed using an e-questionnaire developed Kobo toolbox collect information on socio-demographic, suggestive symptoms, history diagnosis vaccination status. venous blood sample collected from each participant tested immunoglobulin G (Ig-G) antibody titers enzyme-linked immunosorbent assay (ELISA). Seroprevalence 31.1% Regency: 34.2% semi-urban 29.9% urban villages. 55-64 age group demonstrated highest (43.7%; p = 0.00), with a higher risk compared other (aOR 3.79; 95% CI, 1.46-9.85, p<0.05). unvaccinated participants 29.9%. Family accounted 10.6% total seropositive cases. No significant difference observed status, preventive actions, mobility. Higher rather than areas indicates gap health services access. Surveillance improvement through testing, tracing, treatment, particularly lower access services, more robust implementation protocols are necessary.