Vaccination coverage and breakthrough infections of COVID-19 during the second wave among staff of selected medical institutions in India

• DOI: 10.1371/journal.pgph.0000946
• Publication Date: 2023-04-07T17:24:43Z
• Authors: Manju Rahi; Chander Prakash Y...; Sundus Shafat Ahmad; Nitika; Payal Das; Shweta Sharma; Rajendra Kumar Ba...; Debdutta Bhattach...; Pradeep Deshmukh; Amey Dhatrak; Sandeep Dogra; Alex Eapen; Pawan Goel; Nafis Faizi; Siraj A. Khan; Sanjay Kumar Kochar; Aditya Kochar; Ashwani Kumar; Anuj Mundra; Rahul Narang; Kanwar Narain; Krishna Pandey; Sanghamitra Pati; Pankaja Raghav; Ritesh Ranjha; Salman Shah; Kuldeep Singh; Piyoosh Kumar Singh; Raj Kumar Singh; Vijesh Shreedhar ...; Ravinder Soni; Uragayala Sreehari; Sumit Malhotra; Amit Sharma
• Keywords: Pandemic

India experienced the second wave of SARS-CoV-2 infection from April 3 to June 10, 2021. During wave, Delta variant B.1617.2 emerged as predominant strain, spiking cases 12.5 million 29.3 (cumulative) by end surge in India. Vaccines against COVID-19 are a potent tool control and pandemic addition other measures. rolled out its vaccination programme on January 16, 2021, initially with two vaccines that were given emergency authorization–Covaxin (BBV152) Covishield (ChAdOx1 nCoV- 19). Vaccination was started for elderly (60+) front-line workers then gradually opened different age groups. The hit when picking up pace There instances vaccinated people (fully partially) getting infected, reinfections also reported. We undertook survey staff (front line health care supporting) 15 medical colleges research institutes across assess coverage, incidence breakthrough infections, among them 2 July A total 1876 participated, 1484 forms selected analysis after removing duplicates erroneous entries (n = 392). found respondents at time response, 17.6% unvaccinated, 19.8% partially (received first dose), 62.5% fully both doses). Incidence infections 8.7% 801 individuals (70/801) tested least 14 days 2nd dose vaccine. Eight participants reported reinfection overall infected group rate 5.1%. Out (N 349) 243 (69.6%) unvaccinated 106 (30.3%) vaccinated. Our findings reveal protective effect role an essential struggle this pandemic.