Is Exercise Protective Against Influenza-Associated Mortality?

• DOI: 10.1371/journal.pone.0002108
• Publication Date: 2008-05-06T22:39:20Z
• Authors: Chit-Ming Wong; Hak-Kan Lai; Chun-Quan Ou; Sai-Yin Ho; King-Pan Chan; Thuan-Quoc Thach; Lin Yang; Yuen-Kwan Chau; Tai-Hing Lam; Anthony Johnson H...; Joseph Sriyal Mal...
• Keywords: Adult; Science; Exercise - physiology; Comorbidity; Human - complications - mortality - therapy; 796; 03 medical and health sciences; 0302 clinical medicine; Risk Factors; Influenza, Human; Odds Ratio; Humans; Poisson Distribution; Exercise; Life Style; Aged; Aged, 80 and over; Q; R; Middle Aged; Influenza, Human - complications - mortality - therapy; Survival Analysis; Influenza; 3. Good health; Influenza B virus; Influenza A virus; Medicine; Regression Analysis; Research Article

BackgroundLittle is known about the effect of physical exercise on influenza-associated mortality.Methods and FindingsWe collected information habits other lifestyles, socioeconomic demographic status, underlying cause death 24,656 adults (21% aged 30–64, 79% 65 or above) who died in 1998 Hong Kong, weekly proportion specimens positive for influenza A (H3N1 H1N1) B isolations during same period. We assessed excess risks (ER) mortality due to all-natural causes, cardiovascular diseases, respiratory disease among different levels exercise: never/seldom (less than once per month), low/moderate (once month three times week), frequent (four more week) by Poisson regression. also differences ER between groups case-only logistic For all outcomes under study relation each 10% increase A+B, (as reference) was associated with 5.8% 8.5% (P<0.0001), while which were 4.2% 6.4% lower those reference (P<0.001 causes; P = 0.001 cardiovascular; 0.07 mortality). Frequent not from (change −0.8% 1.7%, 0.30 0.73).ConclusionWhen compared never seldom exercise, exercising at low moderate frequency beneficial mortality.