Poststroke Depression and Risk of Recurrent Stroke at 1 Year in a Chinese Cohort Study

• DOI: 10.1371/journal.pone.0046906
• Publication Date: 2012-10-18T12:18:01Z
• Authors: Huai Wu Yuan; Chun Xue Wang; Ning Zhang; Ying Bai; Yu Zhi Shi; Yong Zhou; Yi Long Wang; Tong Zhang; Juan Zhou; Xin Yu; Xin Yu Sun; Zhao Rui Liu; Xing Quan Zhao; Yong Jun Wang
• Keywords: Stroke; Depression; Post-Stroke Depression

Background Studies show that poststroke depression (PSD) increases mortality risk at 1 year. However, whether PSD the of recurrent stroke year remains unclear. This study was to investigate 2 weeks following a could increase Methods and Results multi-centered prospective cohort study. A total 2306 patients with acute were enrolled in our diagnosed according criteria set by Diagnostic Statistical Manual Mental Disorders, fourth edition (DSM-IV). The outcomes followed up via face-to-face or phone interview. 1713 had complete follow-up data, 481 (28.1%) cases 158 (9.2%) cumulative Multivariate logistic regression analysis showed 49% OR PSD, compared without (OR = 1.49, 95%CI: 1.03–2.15). There no significant correlation between anti-depressant drugs 1.96, 95%: CI 0.95–4.04). Conclusions Based on DSM-IV diagnostic criteria, nearly 3 out 10 hospitalized China stroke. is associated higher Our did not find benefit reducing such risk.