Brazilian Multicentre Study on Preterm Birth (EMIP): Prevalence and Factors Associated with Spontaneous Preterm Birth

• DOI: 10.1371/journal.pone.0109069
• Publication Date: 2014-10-09T14:11:11Z
• Authors: Renato Passini; Jose G. Cecatti; Giuliane J. Lajos; Ricardo P. Tedesco; Marcelo L. Nomura; Tabata Z. Dias; Samira M. Haddad; Patricia M. Rehder; Rodolfo C. Pacagn...; Maria L. Costa; Maria H. Sousa
• Keywords: Premature birth

Background Preterm birth rate is increasing and currently a worldwide concern. The purpose of this study was to estimate the prevalence preterm in sample health facilities Brazil identify main risk factors associated with spontaneous births. Methods Findings This multicentre cross sectional on births 20 referral obstetric hospitals case-control component birth. Surveillance implemented at all centres For eligible consenting women, data were collected through post-delivery questionnaire completed information from mother-newborn medical records until death or discharge maximum 60 days post-delivery, whichever came first. estimated OR 95%CI for several predictors. A non-conditional logistic regression analysis then performed independently factors. overall 12.3%. Among them, 64.6% 35.4% therapeutic. In component, 2,682 compared 1,146 term Multivariate analyses identified following as among women least one previous birth: (ORadj = 3.19, 2.30–4.43), multiple pregnancy 29.06, 8.43–100.2), cervical insufficiency 2.93, 1.07–8.05), foetal malformation 2.63, 1.43–4.85), polyhydramnios 2.30, 1.17–4.54), vaginal bleeding 2.16, 1.50–3.11), abortion 1.39, 1.08–1.78). High BMI 0.94, 0.91–0.97) weight gain during gestation 0.92, 0.89–0.95) found be protective Conclusions these high account two thirds them. better understanding utmost importance planning effective measures reduce burden its rates.