Hemodynamic Changes of the Middle Hepatic Vein in Patients with Pulmonary Hypertension Using Echocardiography

• DOI: 10.1371/journal.pone.0121408
• Publication Date: 2015-03-31T13:07:43Z
• Authors: Dan Dan Sun; Chuan Ju Hou; Li Jun Yuan; Yun You Duan; Ying Hou; Fang Ping Zhou
• Keywords: Adult; Heart Defects, Congenital; Male; Science; Hypertension, Pulmonary; Q; R; Hemodynamics; Blood Pressure; Hepatic Veins; Pulmonary Artery; Sensitivity and Specificity; 3. Good health; 03 medical and health sciences; 0302 clinical medicine; Inhalation; Echocardiography; Medicine; Humans; Female; Vascular Resistance; Research Article

The aim of this study was to analyze the changes middle hepatic vein (MHV) spectra in patients with pulmonary hypertension (PH) caused by congenital heart disease (CHD) and determine proper parameters MHV predict PH. Eighty CHD were included, whose artery pressure measured via right catheterization, detected echocardiography. peak value velocity (V) time integral (VTI) waves, including S wave, D wave A at end inspiration. values that predictive PH evaluated their cut-off points determined. Compared control group, V (S), VTI (SVTI), (D), (DVTI) decreased (A), (AVTI), A/S, AVTI/SVTI, A/(S+D), AVTI/ (SVTI+DVTI) increased group. These differences statistically significant (P<0.05). correlation analysis determined ratios AVTI/(SVTI+DVTI) positively correlated mean (r=0.529,0.575,0.438,P<0.001). An ROC curve diagnostic effect A/(S+D) superior other two parameters. On curve, when ratio 0.30, sensitivity 85.37% specificity 75.00% for predicting spectral MHV, AVTI/(SVTI+DVTI), increasing patients. When 0.30 spectra, it had sufficient diagnosing PH, method could be used as a new non-invasive complementary echocardiographic parameter