Maternal Vitamin D Status and Its Related Factors in Pregnant Women in Bangkok, Thailand

• DOI: 10.1371/journal.pone.0131126
• Publication Date: 2015-07-06T18:47:18Z
• Authors: Busadee Pratumvinit; Preechaya Wongkra...; Tuangsit Wataganara; Sithikan Hanyongyuth; Akarin Nimmannit; Somruedee Chatsir...; Kotchamol Manonukul; Kanit Reesukumal
• Keywords: Hypovitaminosis; Cross-sectional study; Calcifediol

Background There are few data focusing on the prevalence of vitamin D deficiency in tropical countries. Objectives We determined status pregnant women and examined factors associated with deficiency. Design Methods A cross-sectional study 147 Thai aged 18–45 years at Siriraj Hospital (a university hospital Bangkok, Thailand) was undertaken. Clinical plasma levels 25-hydroxyvitamin [25(OH)D], intact parathyroid hormone (iPTH), calcium, albumin, phosphate magnesium were obtained delivery. Results The hypovitaminosis [defined as 25(OH)D <75 nmol/L] delivery 75.5% (95% confidence interval (CI), 67.7–82.2%). Of these, insufficiency 50–74.9 found 41.5% CI, 33.4–49.9%) [25(OH)D <50 34.0% 26.4–42.3%) women. mean concentration 61.6±19.3 nmol/L. correlation between iPTH weak (r = –0.29, P<0.01). Factors by multiple logistic regression were: pre-pregnancy body mass index (BMI kg/m2, odds ratio (OR), 0.88, 95% CI 0.80–0.97, P 0.01) season blood collection (winter vs. rainy, OR, 2.62, 1.18–5.85, 0.02). Conclusions Vitamin is common among increased who had a lower BMI whose collected winter. supplementation may need to be implemented routine antenatal care.