Antioxidant Potential of Vespa affinis L., a Traditional Edible Insect Species of North East India

• DOI: 10.1371/journal.pone.0156107
• Publication Date: 2016-05-20T00:30:49Z
• Authors: Prachurjya Dutta; Tapan Dey; Prasenjit Manna; Jatin Kalita
• Keywords: Hydroxyl radical

Introduction Elevated oxidative stress plays an important role in the pathogenesis of health disorders, like arthritis. Traditionally, Vespa affinis L., a common edible insect among many tribes North-East India, is believed to have beneficial extenuating such as The present study investigated molecular mechanism underlying medicinal benefit Aqueous Extract L. (AEVA) against pathophysiology. Methods free radical scavenging activities AEVA were examined DPPH, hydroxyl, and superoxide radicals effect on antioxidant enzyme (GST CAT) was determined using both recombinant proteins human plasma. potential again THP-1 monocytes. Results possesses significant activity evident from superoxide, hydroxyl assay. Incubation (2.5, 5, 7.5, 10 μg/μL) with enzymes, rGST rCAT significantly increased compared those observed corresponding alone or itself. supplementation (5, also stimulates GST CAT when incubated A cell culture confirmed (0.8 1.2 which enhances CAT, reduces intercellular ROS production monocytes treated without H2O2 effects are at par what N-acetyl cysteine-treated cells. Conclusion aqueous extract may mediate its therapeutic stress-associated disorders.