Inverse Correlation between Heart Rate Variability and Heart Rate Demonstrated by Linear and Nonlinear Analysis

• DOI: 10.1371/journal.pone.0157557
• Publication Date: 2016-06-23T14:00:26Z
• Authors: Syed Zaki Hassan ...; Henggui Zhang; Wajid Aziz; Oliver Monfredi; Syed Ali Abbas; Saeed Arif Shah; Syeda Sobia Hassa...; Wasi Haider Butt
• Keywords: Time Factors; Science; Cognitive Neuroscience; Non-contact Physiological Monitoring Technology; Heart rate; Biomedical Engineering; Cardiology; Heart Rate Variability; Geometry; Heart failure; Autonomic Nervous System; FOS: Medical engineering; Sinoatrial node; Quantum mechanics; 03 medical and health sciences; Engineering; 0302 clinical medicine; Respiratory Rate; Heart Rate; Health Sciences; FOS: Mathematics; Animals; Humans; Autonomic nervous system; Internal medicine; Heart rate variability; Sinoatrial Node; Heart Failure; Physics; Q; R; Models, Cardiovascular; Life Sciences; Brain-Computer Interfaces in Neuroscience and Medicine; Correlation; Nonlinear Dynamics; Analysis and Applications of Heart Rate Variability; Physical Sciences; Nonlinear system; Blood pressure; Medicine; Rabbits; Cardiology and Cardiovascular Medicine; Mathematics; Research Article; Neuroscience

The dynamical fluctuations in the rhythms of biological systems provide valuable information about underlying functioning these systems. During past few decades analysis cardiac function based on heart rate variability (HRV; variation R wave to intervals) has attracted great attention, resulting more than 17000-publications (PubMed list). However, it is still controversial underling mechanisms HRV. In this study, we performed both linear (time domain and frequency domain) nonlinear HRV data acquired from humans animals identify relationship between (HR). consists following groups: (a) human normal sinus rhythm (n = 72); (b) congestive failure 44); (c) rabbit sinoatrial node cells (SANC; n 67); (d) conscious rat 11). animal at variant pathological conditions, techniques showed an inverse correlation HR, supporting concept that dependent therefore, cannot be used ordinary manner analyse autonomic nerve activity a heart.