Soluble Milk Protein Supplementation with Moderate Physical Activity Improves Locomotion Function in Aging Rats

• DOI: 10.1371/journal.pone.0167707
• Publication Date: 2016-12-14T19:03:57Z
• Authors: Aude Lafoux; Charlotte Baudry; Cécile Bonhomme; Pascale Le Ruyet; Corinne Huchet
• Keywords: Treadmill; Forelimb

Aging is associated with a loss of muscle mass and functional capacity. Present study was designed to compare the impact specific dairy proteins on muscular function or without low-intensity physical activity program treadmill in an aged rat model. We investigated effects nutritional supplementation, five days week over 2-month period slow digestible protein, casein fast proteins, whey soluble milk strength locomotor parameters sedentary active Wistar RjHan rats (17-19 months age). An extensive gait analysis performed before after protein supplementation. After two administration program, force evaluated using grip test, spontaneous open-field by sampling. When were supplemented exercise, only minor different diets locomotion observed: higher group improvement stride frequencies protein. By contrast, supplementation just more effective at improving overall skeletal old compared casein. For increase open field enhancement static dynamic groups observed any differences forelimb strength. These results suggest that consumption as bolus immediately low intensity may be suitable intervention prevent decline strengthen interest analyze longitudinal aspect rodents.