Predictors of Health-Related Quality of Life in Patients with Co-Morbid Diabetes and Chronic Kidney Disease

• DOI: 10.1371/journal.pone.0168491
• Publication Date: 2016-12-19T19:00:17Z
• Authors: Edward Zimbudzi; Clement Lo; Sanjeeva Ranasinha; Martin Gallagher; Gregory Fulcher; Peter G. Kerr; Grant Russell; Helena Teede; Tim Usherwood; Rowan Walker; Sophia Zoungas
• Keywords: Cross-sectional study

Background People living with diabetes and chronic kidney disease (CKD) experience compromised quality of life. Consequently, it is critical to identify understand factors influencing their health-related life (HRQoL). This study examined associated HRQoL among patients CKD. Methods A cross sectional adults comorbid CKD (eGFR <60 mL/min/1.73m2) recruited from renal clinics four large tertiary referral hospitals in Australia was performed. Each participant completed the Kidney Disease Quality Life (KDQoL ™ -36) questionnaire, which comprised two composite measures physical mental health 3 specific subscales possible scores ranging 0 100 higher values indicating better HRQoL. Demographic clinical data were also collected. Regression analyses performed determine relationship between potential predictor factors. Results total 308 studied a mean age 66.9 (SD = 11.0) years 70% males. Mean for summary, symptom/problem list, effects burden scales 35.2, 47.0, 73.8, 72.5 59.8 respectively. Younger lower all except summary. Female gender, obese or normal weight rather than overweight, smoking one more subscales. Scores progressively advanced stage (p<0.05) Conclusion In CKD, younger summary female stages Identifying these will inform timely implementation interventions improve patients.