Pregnancy incidence and intention after HIV diagnosis among women living with HIV in Canada

Unintended Pregnancy Rate ratio
DOI: 10.1371/journal.pone.0180524 Publication Date: 2017-07-20T13:41:49Z
ABSTRACT
Pregnancy incidence rates among women living with HIV (WLWH) have increased over time due to longer life expectancy, improved health status, and access prevention benefits of combination antiretroviral therapy (cART). However, it is unclear whether intended or unintended pregnancies are contributing observed increases.We analyzed retrospective data from the Canadian Women's Sexual Reproductive Health Cohort Study (CHIWOS). Kaplan-Meier methods GEE Poisson models were used measure cumulative rate pregnancy after diagnosis overall, by intention. We multivariable logistic regression examine independent correlates most recent/current pregnancy.Of 1,165 WLWH included in this analysis, 278 (23.9%) reported 492 diagnosis, 60.8% which unintended. Unintended (24.6 per 1,000 Women-Years (WYs); 95% CI: 21.0, 28.7) was higher than (16.6 WYs; 13.8, 20.1) (Rate Ratio: 1.5, 1.2-1.8). who initiated cART before during (29.1 1000 WYs 25.1, 33.8) not on (11.9 9.5, 14.9) 2.4, 2.0-3.0). Women current recent (vs. pregnancy) had adjusted odds being single (AOR: 1.94; 1.10, 3.42), younger at conception 0.95 year increase, 0.90, 0.99), born Canada 2.76, 1.55, 4.92).Nearly one-quarter 61% all as Integrated reproductive care programming required better support optimize planning outcomes prevent pregnancy.
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