Combined epidural-general anesthesia was associated with lower risk of postoperative complications in patients undergoing open abdominal surgery for pheochromocytoma: A retrospective cohort study

• DOI: 10.1371/journal.pone.0192924
• Publication Date: 2018-02-21T13:41:54Z
• Authors: Nan Li; Hao Kong; Shuang-Ling Li; Sai-Nan Zhu; Dong-Xin Wang
• Keywords: Adult; Anesthesia, Epidural; Male; Science; Pheochromocytoma; Anesthesia, General; 03 medical and health sciences; Postoperative Complications; 0302 clinical medicine; Risk Factors; Abdomen; Humans; Retrospective Studies; Incidence; Q; R; Middle Aged; 3. Good health; Hospitalization; Logistic Models; Multivariate Analysis; Medicine; Female; Research Article

Background Current evidences show that regional anesthesia is associated with decreased risk of complications after major surgery. However, the effects combined regional-general remain controversial. The purpose our study was to analyze impact (combined epidural-general vs. general anesthesia) on postoperative in patients undergoing open surgery for pheochromocytoma. Methods This a retrospective cohort study. 146 who underwent pheochromocytoma (100 received and 46 Peking University First Hospital from January 1, 2002 December 31, 2015 were enrolled. primary outcome occurrence during hospital stay Multivariate Logistic regression models used association between choice anesthetic method complications. Results 17 (11.6%) developed stay. incidence lower than those (6% [6/100] 23.9% [11/46], P = 0.006). analysis showed use (OR 0.219, 95% CI 0.065–0.741; 0.015) risk, whereas male gender 5.213, 1.283–21.177; 0.021) perioperative blood transfusion 25.879; 3.130–213.961; 0.003) higher Conclusions For pheochromocytoma, may decrease