Screening for obstructive sleep apnea among hospital outpatients

• DOI: 10.1371/journal.pone.0198315
• Publication Date: 2018-05-30T17:39:45Z
• Authors: Michel Hug; Katrin Uehli; Stig Solbach; Stefanie Brighent...; Selina Dürr; Sabrina Maier; Jörg Daniel Leuppi; David Miedinger
• Keywords: Gold standard (test); Apnea–hypopnea index

Background Obstructive sleep apnea syndrome (OSAS) is common in adults. People with OSAS have a higher risk of experiencing traffic accidents and occupational injuries (OIs). We aimed to clarify the diagnostic performance three-channel screening device (ApneaLinkTM) compared gold standard full-night attended polysomnography (PSG) among hospital outpatients not referred for sleep-related symptoms. Furthermore, we determine whether manual revision ApneaLinkTM autoscore enhanced performance. Methods investigated 68 patients OI 44 without recruited from University Hospital Basel emergency room, using cross-sectional study design. Participating spent one night at home within 2 weeks slept laboratory. reanalyzed all data after revision. Results identified significant correlations between apnea-hypopnea index (AHI) AHI derived by PSG (r = 0.525; p <0.001) oxygen desaturation (ODI) that 0.722; <0.001). The showed sensitivity specificity 82% when comparing ≥5 cutoff and/or ODI ≥15 PSG. In Bland Altman plots mean difference was 2.75 SD ± 8.80 (β 0.034), revised score -1.50 9.28 0.060). Conclusions demonstrated good (full-night PSG). However, revealed substantial fluctuations respectively manually score. This spread clinical perspective large, therefore results be interpreted caution. our findings suggest there no benefit revising autoscore.