Distribution modeling and lineage diversity of the chytrid fungus Batrachochytrium dendrobatidis (Bd) in a central African amphibian hotspot

• DOI: 10.1371/journal.pone.0199288
• Publication Date: 2018-06-20T17:56:04Z
• Authors: Courtney A. Miller; Geraud Canis Tass...; Mary M. P. Ekane; Matthew Robak; Paul R. Sesink Clee; Corinne Richards-...; Eric B. Fokam; Nkwatoh Athanasiu...; Nicola M. Anthony
• Keywords: Chytridiomycosis; Chytridiomycota; Lineage (genetic); Emerging infectious disease; Phylogenetic diversity

The amphibian disease chytridiomycosis in amphibians is caused by the chytrid fungus Batrachochytrium dendrobatidis (Bd) and has resulted dramatic declines extinctions of populations worldwide. A hypervirulent, globally-dispersed pandemic lineage (Bd-GPL) thought to be largely responsible for population extinctions, although numerous endemic lineages have also been found. Recent reports linked emergence Bd Cameroon, a major hotspot African diversity. However, it not known whether Bd-GPL or other found this region. This study therefore aims examine diversity region predict distribution pathogen under current future climate conditions using data from historical records. Almost 15% (52/360) individuals tested positive standard quantitative PCR diagnostic. Infected were at all eight sites sampled study. Species models generated BIOMOD2 indicate that areas with highest predicted environmental suitability occur Cameroon highlands several protected throughout country. These high are projected shift decrease size change. montane regions remain highly suitable. Phylogenetic analysis ITS sequences obtained set samples most fall within while remainder group isolates either Brazil South Korea. Although more depth phylogenetic analyses needed, identification emphasizes need continue monitor develop appropriate conservation strategies prevent its further spread.