Association between body mass index and 1-year outcome after acute myocardial infarction

• DOI: 10.1371/journal.pone.0217525
• Publication Date: 2019-06-14T17:34:07Z
• Authors: Dae-Won Kim; Sung-Ho Her; Ha Wook Park; Mahn-Won Park; Kiyuk Chang; Wook Sung Chung; Ki Bae Seung; Tae Hoon Ahn; Myung Ho Jeong; Seung-Woon Rha; Hyo-Soo Kim; Hyeon Cheol Gwon; In Whan Seong; Kyung Kuk Hwang; Shung Chull Chae; Kwon-Bae Kim; Young Jo Kim; Kwang Soo Cha; Seok Kyu Oh; Jei Keon Chae
• Keywords: Obesity paradox; Clinical endpoint

Objectives Beneficial effects of overweight and obesity on mortality after acute myocardial infarction (AMI) have been described as "Body Mass Index (BMI) paradox". However, the BMI is still debate. We analyzed association between 1-year clinical outcomes AMI. Methods Among 13,104 AMI patients registered in Korea Acute Myocardial Infarction Registry-National Institute Health (KAMIR-NIH) November 2011 December 2015, 10,568 who eligible for this study were classified into 3 groups according to (Group 1; < 22 kg/m2, ≤ Group 2 26 3; ≥ kg/m2). The primary end point was all cause death at 1 year. Results Over median follow-up 12 months, event occurred more frequently than (primary endpoint: adjusted hazard ratio [aHR], 1.537; 95% confidence interval [CI] 1.177 2.007, p = 0.002). Especially, cardiac played a major role effect (aHR, 1.548; 1.128 2.124, 0.007). Conclusions Higher appeared be good prognostic factor This result suggests that higher or might confer protective advantage over life-quality