Cost utility analysis of end stage renal disease treatment in Ministry of Health dialysis centres, Malaysia: Hemodialysis versus continuous ambulatory peritoneal dialysis

• DOI: 10.1371/journal.pone.0218422
• Publication Date: 2019-10-23T17:29:30Z
• Authors: Naren Kumar Surendra; Mohd Rizal Abdul ...; Lai Seong Hooi; Sunita Bavanandan; Fariz Safhan Moha...; Shahnaz Shah Fird...; Ong Loke Meng; Abdul Halim Abdul...
• Keywords: Christian ministry; Cost–utility analysis

In Malaysia, there is exponential growth of patients on dialysis. Dialysis treatment consumes a considerable portion healthcare expenditure. Comparative assessment their cost effectiveness can assist in providing rational basis for preference dialysis modalities.A utility study hemodialysis (HD) and continuous ambulatory peritoneal (CAPD) was conducted from Ministry Health (MOH) perspective. A Markov model also developed to investigate the increasing uptake incident CAPD 55% 60% versus current practice 40% five-year temporal horizon. scenario with 30% measured. The costs utilities were sourced published data which collected as part this study. transitional probabilities survival estimates obtained Malaysia Transplant Registry (MDTR). outcome measures per life year (LY), quality adjusted LY (QALY) incremental ratio (ICER) model. Sensitivity analyses performed.LYs saved HD 4.15 years 3.70 CAPD. QALYs 3.544 3.348 Cost RM39,791 RM37,576 QALY gained RM46,595 RM41,527 showed commencement 50% ESRD initial modality very cost-effective within MOH. Reduction use associated higher small devaluation QALYs.These findings suggest provision both modalities fiscally feasible; would be more cost-effective.