The cresty neck score is an independent predictor of insulin dysregulation in ponies

• DOI: 10.1371/journal.pone.0220203
• Publication Date: 2019-07-24T17:43:12Z
• Authors: Danielle M. Fitzg...; Stephen T. Anderson; Martin N. Sillence; Melody A. de Laat
• Keywords: Hyperinsulinemia; Laminitis; Basal (medicine)

Generalized obesity, regional adiposity, hyperinsulinemia and hypertriglyceridemia are all potential indicators of equine metabolic syndrome (EMS). This study aimed to assess the relationship between morphometric measurements body condition hormone concentrations in ponies, with without a neck crest or generalised obesity. Twenty-six ponies were assigned score (BCS) cresty (CNS). Height, girth, taken. An oral glucose test (OGT; 0.75g dextrose/kg BW) was performed blood samples collected prior 2 hours post dosing. Basal analysed for glucose, serum insulin, triglyceride leptin, plasma HMW adiponectin concentrations. Post-prandial insulin concentration. The grouped as having a) normal fleshy status (BCS ≤7 CNS ≤2; n = 10); b) high CNS, but obesity ≥3; 11), c) being obese ≥8 ≥1; 5). Responses OGT indicated that both insulin-dysregulated included cohort. positively associated (P<0.035) ≥ 3 had 5 times greater odds insulin-dysregulated. group response than those normal/fleshy (P 0.006), whereas did not differ from other two groups. negatively correlated post-prandial (r -0.5, P 0.009), well decreased compared 0.05). Cresty more predictive dysregulation BCS, this may be relevant diagnosis EMS. Adiponectin also measure is independent condition.