Intrinsic and extrinsic factors associated with sputum characteristics of presumed tuberculosis patients

• DOI: 10.1371/journal.pone.0227107
• Publication Date: 2019-12-27T13:29:18Z
• Authors: Fred Orina; Moses Mwangi; Hellen Meme; Benson Kitole; Evans Amukoye
• Keywords: History of tuberculosis

Background Sputum remains the most preferred specimen for detection of Mycobacterium tuberculosis due to its non-invasive method production. Good quality sputum is essential accurate diagnosis pulmonary (PTB). It therefore imperative assess factors that are related production best quality. Objective We assessed intrinsic and extrinsic characteristics presumed patients they produced. Methods This was a cross-sectional study in which consenting enrolled were subjected medical examination structured questionnaire administered collect clinical history, demographic information, environmental behavioral characteristics. The participants instructed on how spot morning specimens macroscopic microscopic assessment determine any association. Results A total 309 into with an even distribution gender (50.5% males). Of these, 202 (65.3%) submitted both analysis. On examination, 70% 68% characterized as good (Purulent/mucoid). associated (p<0.05) included factors. included: difficulty breathing, presence conjunctivitis knowledge disease whereas only factor time taken by patient seek treatment after occurrence TB symptoms. Conclusion Both affected produced patients. Clinical including conjunctivitis, breathing delay seeking important determined specimens, while did not compel produce disease.