Prevalence of anemia in patients with chronic kidney disease in Japan: A nationwide, cross-sectional cohort study using data from the Japan Chronic Kidney Disease Database (J-CKD-DB)

• DOI: 10.1371/journal.pone.0236132
• Publication Date: 2020-07-20T17:26:12Z
• Authors: Tadashi Sofue; Naoki Nakagawa; Eiichiro Kanda; Hajime Nagasu; Kunihiro Matsushita; Masaomi Nangaku; Shoichi Maruyama; Takashi Wada; Yoshio Terada; Kunihiro Yamagata; Ichiei Narita; Motoko Yanagita; Hitoshi Sugiyama; Takashi Shigematsu; Takafumi Ito; Kouichi Tamura; Yoshitaka Isaka; Hirokazu Okada; Kazuhiko Tsuruya; Hitoshi Yokoyama; Naoki Nakashima; Hiromi Kataoka; Kazuhiko Ohe; Mihoko Okada; Naoki Kashihara
• Keywords: Cross-sectional study

The Japan Chronic Kidney Disease Database (J-CKD-DB) is a nationwide clinical database of patients with chronic kidney disease (CKD) based on electronic health records. objective this study was to assess the prevalence anemia and utilization rate erythropoiesis-stimulating agents (ESAs) in Japanese CKD.In total, 31,082 adult outpatients estimated glomerular filtration rates 5-60 ml/min/1.73 m2 seven university hospitals were included analysis. proportions CKD stages G3b, G4, G5 23.5%, 7.6%, 3.1%, respectively.The mean (standard deviation) hemoglobin level male 13.6 (1.9) g/dl, which significantly higher than female (12.4 (1.6) g/dl). levels 11.4 (2.1) g/dl stage G4 11.2 (1.8) G5. prevalences 40.1% 60.3% Logistic regression analysis showed that diagnoses G3b (adjusted odds ratio [95% confidence interval]: 2.32 [2.09-2.58]), (5.50 [4.80-6.31]), (9.75 [8.13-11.7]) associated increased anemia. ESAs 7.9% 22.4% G5.We determined using data from cohort study.