What is AIDS in the Amazon and the Guianas in the 90-90-90 era?

• DOI: 10.1371/journal.pone.0236368
• Publication Date: 2020-07-24T17:27:28Z
• Authors: Mathieu Nacher; Antoine Adenis; Basma Guarmit; Aude Lucarelli; Denis Blanchet; Magalie Demar; Felix Djossou; Philippe Abboud; Loïc Epelboin; Pierre Couppié
• Keywords: Opportunistic infection; AIDS-Related Opportunistic Infections; Esophageal candidiasis; Cryptococcal meningitis

In the past decade, new diagnostic methods and strategies have appeared, HIV testing efforts generalization of antiretroviral therapy may influenced number opportunistic diagnoses mortality HIV-infected patients. To test this hypothesis we compiled data on top infections causes early death in cohort French Guiana.HIV-infected persons followed Cayenne, Kourou, Saint Laurent du Maroni hospitals from 2010 to 2019 were studied. Annual incidence different annual deaths are compiled. For patients with calculated proportion deaths.At time analysis, among 2 459 patients, (treated untreated) 90% had a viral load <400 copies, 91% treatment, 94.2% treatment for over 6 months undetectable loads. Only 9% CD4 counts under 200 per mm3. Histoplasmosis clearly remained most frequent (128 cases) infection by cerebral toxoplasmosis (63 esophageal candidiasis (41 cases). Cryptococcal meningitis was ranked 5th as tuberculosis (31 The trend sharp decline continued (3.9% patients).Despite successes antiretrovirals, presenting advanced still common they at risk dying. Improved diagnosis, notably systematic screening appropriate tools important areas potential progress.