Dynamic foraminal dimensions during neck motion 6.5 years after fusion and artificial disc replacement

• DOI: 10.1371/journal.pone.0237350
• Publication Date: 2020-08-11T18:10:10Z
• Authors: Sherwin Azad; Daniel Oravec; Timothy Baumer; Andrew Schildcrout; Parnell White; Azam Basheer; Michael J. Bey; Stephen W. Bartol; Victor Chang; Yener N. Yeni
• Keywords: Adult; Male; Total Disc Replacement; Science; Intervertebral Disc Degeneration; 03 medical and health sciences; Imaging, Three-Dimensional; 0302 clinical medicine; Humans; Postoperative Period; Range of Motion, Articular; Aged; Q; R; Middle Aged; Biomechanical Phenomena; Spinal Fusion; Treatment Outcome; Cervical Vertebrae; Medicine; Female; Tomography, X-Ray Computed; Research Article; Diskectomy; Follow-Up Studies

To compare changes in foraminal motion at two time points post-surgery between artificial disc replacement (ADR) and anterior cervical discectomy and fusion (ACDF).Eight ACDF and 6 ADR patients (all single-level C5-6) were tested at 2 years (T1) and 6.5 years (T2) post-surgery. The minimum foraminal height (FH.Min) and width (FW.Min) achieved during neck axial rotation and extension, and the range of these dimensions during motion (FH.Rn and FW.Rn, respectively) were measured using a biplane dynamic x-ray system, CT imaging and model-based tracking while patients performed neck axial rotation and extension tasks. Two-way mixed ANOVA was employed for analysis.In neck extension, significant interactions were found between year post-surgery and type of surgery for FW.Rn at C5-6 (p<0.006) and C6-7 (p<0.005), and for FH.Rn at C6-7 (p<0.01). Post-hoc analysis indicated decreases over time in FW.Rn for ACDF (p<0.01) and increases in FH.Rn for ADR (p<0.03) at the C6-7 adjacent level. At index level, FW.Rn was comparable between ACDF and ADR at T1, but was smaller for ACDF than for ADR at T2 (p<0.002). In axial rotation, differences were found between T1 and T2 but did not depend on type of surgery (p>0.7).Changes were observed in the range of foraminal geometry at adjacent levels from 2 years to 6.5 years post-surgery that were different between ACDF and ADR for neck extension. These changes are contrary to the notion that motion at adjacent levels continue to increase following ACDF as compared to ADR over the long term.