Usability of graphene oxide as a mycotoxin binder: In vitro study

• DOI: 10.1371/journal.pone.0239479
• Publication Date: 2020-09-23T17:34:51Z
• Authors: Pavel Horky; Eva Venusova; Tereza Aulichova; Andrea Ridoskova; Jiri Skladanka; Sylvie Skalickova
• Keywords: 2. Zero hunger; Aflatoxin B1; Science; Q; R; Food Contamination; 04 agricultural and veterinary sciences; In Vitro Techniques; Mycotoxins; Animal Feed; Nanostructures; 0404 agricultural biotechnology; Gastrointestinal Absorption; Medicine; Animals; Humans; Zearalenone; Digestion; Graphite; Adsorption; Trichothecenes; Triticum; Research Article

Mycotoxin management in agriculture is an essential challenge for maintaining the health of both animals and humans. Choosing right adsorbent still a question many breeders important criterion feed manufacturers. New adsorbents are being sought. Graphene oxide promising material field nanotechnology, which excels its adsorption properties. Presented vitro study investigates graphene binding mycotoxins from crushed wheat. The results show that has capacity aflatoxin 0.045 mg/g, zearalenone 0.53 mg/g deoxynivalenol 1.69 at 37° C. In simulation wheat digestion showed rapid during gastric phase. Of minerals, Mg, Cu Zn were most adsorbed. applied dose 10 caused only slight inhibition digestive enzymes α-amylase trypsin compared to pepsin lipase. indicated suitability aflatoxin, deoxynivalenol.