Tuberculosis screening in household contacts of pulmonary tuberculosis patients in an urban setting

• DOI: 10.1371/journal.pone.0240594
• Publication Date: 2020-10-15T18:49:11Z
• Authors: Banurekha Velayutham; Lavanya Jayabal; Basilea Watson; Saraswathy Jagade...; Dhanalakshmi Anga...; Priscilla Rebecca; Bella Devaleenal; Dina Nair; Srikanth Tripathy; Sriram Selvaraju
• Keywords: Adult; Male; Adolescent; Urban Population; Science; Antitubercular Agents; India; 03 medical and health sciences; Clinical Research; Humans; Mass Screening; Registries; Child; Tuberculosis, Pulmonary; Family Characteristics; 0303 health sciences; Q; R; Health Plan Implementation; Antibiotic Prophylaxis; 3. Good health; Child, Preschool; Medicine; Feasibility Studies; Female; Contact Tracing; Research Article; Follow-Up Studies; Program Evaluation

Household contacts (HHC) of tuberculosis (TB) patients are at risk of TB infection and disease. The study assessed the utility of "Household contact card and register" for screening of HHC of pulmonary TB (PTB) patients for TB and explored the reasons for HHC not being screened and followed-up.The "Household contact card and register" was implemented by the Health Care Workers (HCW) of the TB Control Programme in Chennai District for screening HHC of index PTB patients initiated on treatment between June and August, 2018. Contacts were required to be screened within 2 months of treatment initiation of the index patient. Details collected included age, gender, smoking, alcohol use, immunosuppressive conditions and TB treatment. Symptom screening along with chest radiograph and or sputum examination was attempted. Follow-up TB screening at 6 and 12 months were performed. Screening of HHC was compared pre and post implementation phase. Proportions were computed for the data analysed.HHC information was documented for 93% (1268/1364) of Index PTB patients. The main reasons of non-listing of HHC in 96 PTB patients were HCW non-availability or non-co-operation of the HHC. There were 2150 (80%) contacts who were screened for TB. Inconvenient time, feeling healthy, stigma, out-station visit were the main reasons for 537 contacts not undergoing TB screening. Anti-TB treatment was initiated in 21 (1%) of contacts diagnosed with TB. Preventive therapy was initiated in 59% (81/138) of contacts aged <6 years. The screening of HHC improved from 36% to 80% during the implementation phase. Follow-up TB screening at 12 months was performed in 50% of HHC and 2 incident TB cases were identified."Household contact card and register" is a useful tool for HCWs for TB screening in HHC of PTB patients. Reasons for non-adherence to contact screening needs to be addressed.