Oxygen saturation as a predictor of mortality in hospitalized adult patients with COVID-19 in a public hospital in Lima, Peru

• DOI: 10.1371/journal.pone.0244171
• Publication Date: 2020-12-28T19:14:36Z
• Authors: Fernando Mejía; Carlos Medina; Enrique Cornejo; Enrique Morello; Sergio Vásquez; Jorge Alave; Alvaro Schwalb; Germán Málaga
• Keywords: Oxygen Saturation

Introduction Peru is among the top ten countries with highest number of coronavirus disease 2019 (COVID-19) cases worldwide. The aim study was to describe clinical features hospitalized adult patients COVID-19 and determine prognostic factors associated in-hospital mortality. Methods We conducted a retrospective cohort admitted Hospital Cayetano Heredia; tertiary care hospital in Lima, Peru. primary outcome Multivariate Cox proportional hazards regression used identify independently Results A total 369 (median age 59 years [IQR:49–68]; 241 (65.31%) male) were included. Most (68.56%) reported at least one comorbidity; more frequently: obesity (42.55%), diabetes mellitus (21.95%), hypertension (21.68%). median duration symptoms prior admission 7 days (IQR: 5–10). Reported mortality 49.59%. By multiple regression, oxygen saturation (SaO 2 ) values less than 90% on correlated mortality, presenting 1.86 (95%CI: 1.02–3.39), 4.44 2.46–8.02) 7.74 4.54–13.19) times greater risk death for SaO 89–85%, 84–80% <80%, respectively, when compared >90%. Additionally, >60 1.88 Conclusions Oxygen below strong predictor COVID-19. In settings limited resources, efforts reduce should focus early identification hypoxemia timely access care.