Comparison of functional-oil blend and anticoccidial antibiotics effects on performance and microbiota of broiler chickens challenged by coccidiosis

• DOI: 10.1371/journal.pone.0270350
• Publication Date: 2022-07-06T17:33:52Z
• Authors: Paula Gabriela da...; Pedro Torres; Tatiany Aparecida...; Vilmar Benetti Filho; Lucélia Hauptli; Glauber Wagner; Douglas Haese; Carolina D’ávila ...; Priscila de Olive...
• Keywords: Eimeria acervulina; Eimeria maxima; Virginiamycin; Andrographis Paniculata; Tylosin; Feed additive; Completely randomized design; Monensin

This study aimed to compare the effects of different levels cashew nutshell liquid (CNSL) and castor oil (CNSL-castor oil) with growth-promoting antibiotics associated anticoccidials in broiler chickens challenged coccidiosis. In this work, 2520 one-day-old male chicks (Cobb) were randomly assigned 84 pens, containing 30 birds each. The experimental design was completely randomized, seven treatments: enramycin (8 ppm), virginiamycin (16.5 tylosin (55 ppm); doses CNSL-castor (0.5, 0.75, 1.00 kg/t); a control diet (without additives). All treatments received semduramicin + nicarbazin (500 g/t; Aviax® Plus) from 0 28 d monensin sodium (100 ppm; Elanco) 29 35 days age, when feed without antibiotics. challenge introduced at 14 age by inoculating sporulated Eimeria tenella, acervulina, maxima oocysts via oral gavage. addition performance parameters, intestinal contents collected 42 for microbiota analysis sequencing 16s rRNA V3 V4 regions using Illumina MiSeq platform. Taxonomy SILVA database (v. 138) QIIME2 software 2020.11). After one week challenge, broilers that had higher body weight gain (BWG) than those group (p < 0.05), while other presented intermediate values. At d, BWG lower control, CNSL-Castor 0.5 kg/t, enramycin, treatment. inclusion concentrations 0.75 1 kg/t acted as an treatment 0.05). For alpha diversity, Shannon index, it possible observe effect substantial diversity d. Firmicutes phylum highest abundance, values between 84.33% 95.16% Tylosin showed better indices treatments. similar results virginiamycin. Furthermore, modulator microbiota, reducing abundance pathogenic bacteria.