Responses towards eyefluke (Diplostomum pseudospathaceum) in different genetic lineages of rainbow trout

• DOI: 10.1371/journal.pone.0276895
• Publication Date: 2022-10-27T17:48:48Z
• Authors: Asma M. Karami; Yajiao Duan; Per W. Kania; Kurt Buchmann
• Keywords: Ichthyophthirius multifiliis

Marker-assisted selective breeding of fish with higher levels resistance towards specific pathogens may improve health, but the impact host genotype on susceptibility to multiple pathogen infections is still poorly investigated. This study examined in rainbow trout Oncorhynchus mykiss infection eye fluke Diplostomum pseudospathaceum. We used genetically selected trout, carrying SNPs associated parasitic ciliate Ichthyophthirius multifiliis, and exposed cercariae. showed that partly resistant I. multifiliis were more susceptible invasion. The expression immune relevant genes (encoding innate adaptive factors) was also affected as these genotypes responded less strongly a secondary infection. complexity genome architecture disease discussed.