Association of red cell distribution width/albumin ratio with intraoperative blood transfusion in cervical cancer patients

• DOI: 10.1371/journal.pone.0277481
• Publication Date: 2022-11-18T18:28:04Z
• Authors: Ji-Hoon Sim; Dong-Min Jang; Hyun-Seok Cho; Jong Yeon Park; Woo-Jong Choi
• Keywords: Erythrocyte Indices; Science; Q; R; Uterine Cervical Neoplasms; 3. Good health; 03 medical and health sciences; 0302 clinical medicine; Albumins; Medicine; Humans; Female; Blood Transfusion; Research Article; Retrospective Studies

Background Although minimally invasive surgical techniques have reduced intraoperative bleeding, the risk of transfusion exists. However, few studies evaluated factors for in radical hysterectomy. We aimed to evaluate association between preoperative red cell distribution width/albumin ratio (RDW/albumin) and cervical cancer patients. Methods analyzed 907 patients who underwent hysterectomy June 2006 February 2015. Logistic regression Cox analyses were performed determine mortality at 5-year overall. Net reclassification improvement (NRI) integrated identification (IDI) verify model upon addition RDW/albumin. Results RDW/albumin was an independent factor (odds [OR]: 1.34, 95% confidence interval [CI]: 1.02–1.77, p = 0.035). Additionally, body mass index, operation time, laparoscopic surgery, total fluids, synthetic colloid transfusion. (hazard [HR]: 1.51, CI: 1.07–2.14, 0.020), overall (HR: 1.48, 1.06–2.07, 0.021). NRI IDI showed discriminatory power (p<0.001 0.046, respectively). Conclusions might be a significant