Adverse events of COVID-19 vaccines in pregnant and postpartum women in Brazil: A cross-sectional study

• DOI: 10.1371/journal.pone.0280284
• Publication Date: 2023-01-13T18:31:09Z
• Authors: Dimas Tadeu Covas; Ariane de Jesus L...; Carolina Zampirol...; Rafaela Vansan Fe...; Ramon Gonçalves P...; Guilherme Silva J...
• Keywords: Cross-sectional study

Background By the fact that pregnant and postpartum women are currently using COVID-19 vaccines, ensure their safety is critical. So, more evidence crucial to include this new technology vaccine’s calendar develop public policies regarding support training of Health Care Personnel. This study aims describe adverse events (AE) vaccines in early stage vaccination campaign Brazil. Methods An observational cross-sectional data from Brazilian surveillance information system characterize AE (Sinovac/Butantan, Pfizer/BioNTech, AstraZeneca Janssen) April August 2021. Frequency incidence rate for were assessed. Results 3,333 following immunization reported population. was 309.4/100,000 doses (95% CI 297.23, 321.51). Within available, Sinovac/Butantan had lowest (74.08/100,000 doses; 95% 63.47, 84.69). Systemic most frequent notified (82.07%), followed by local (11.93%) maternal (4.74%), being them classified as non-severe (90.65%). Conclusion Our results corroborate recommendation these groups. Even though, further studies appraising a longer observation time still needed provide broader aspect under use