Associations of hypertension and antenatal care-seeking with perinatal mortality: A nested case-control study in rural Bangladesh

• DOI: 10.1371/journal.pone.0287622
• Publication Date: 2024-07-22T17:29:46Z
• Authors: Allyson P. Bear; Wendy L. Bennett; Joanne Katz; Kyu Han Lee; Atique Iqbal Chow...; Sanwarul Bari; Shams El Arifeen; Emily S. Gurley
• Keywords: Maternal death; Prenatal Care; Gestational hypertension; Nested case-control study

Maternal hypertension may be an underrecognized but important risk factor for perinatal death in low resource settings. We investigated the association of maternal and mortality rural Bangladesh. This nested, matched case-control study used data from a 2019 cross-sectional survey demographic surveillance database Baliakandi, randomly each pregnancy ending with five pregnancies which neonate survived beyond seven days based on age, education, wealth quintile. estimated associations antenatal care-seeking self-reported using conditional logistic regression median interquartile ranges to assess mediation care by timing or frequency. Among 191 cases 934 controls, prevalence was 14.1% among 7.7% controls. Compared no diagnosis, probability significantly higher women pre-gestational diagnosis (OR 2.90, 95% CI 1.29, 6.57), not during 1.68, 0.98, 2.98). found between number contacts (p = 0.66). who experienced death, 78% had their first contact sixth seventh month gestation. Hypertension more common experience death. Greater effort prevent prior conception provide early maternity could improve outcomes