Lower odds of COVID-19-related mortality in hospitalised patients with type II diabetes mellitus: A single-centre study

• DOI: 10.1371/journal.pone.0287968
• Publication Date: 2023-11-17T18:24:17Z
• Authors: Jonathan Mina; Nadia L. Samaha; Mohamad Fleifel; Janane Nasr; Tony Haykal; Hani Dimassi; Ranime Harb; Ghida El Hout; Elissar Franjieh; Ahmad Mahdi; Jacques Mokhbat; Anna Farra; Rola Husni
• Keywords: SARS-CoV-2; Science; Q; R; COVID-19; 3. Good health; Hospitalization; Intensive Care Units; Diabetes Mellitus, Type 2; Troponin T; Medicine; Humans; Research Article; Aged; Retrospective Studies

COVID-19 infection in patients with type 2 diabetes mellitus (T2DM) -a chronic illness Lebanon-is not well described.This was a single-centre retrospective observational study of 491 patients, including 152 T2DM, who were hospitalised for between 20 August 2020 and 21 April 2021. Data on clinical characteristics, laboratory radiological findings outcomes collected from the electronic medical records. Clinical characteristics in-hospital mortality without T2DM infected using multivariate analysis compared.Patients significantly older than those (mean age, 68.7 vs. 60.3 years). Patients more likely to present body temperature <38.3°C (83.9% 69.9%) less chest pain (3.9% 9.1%) sore throat (2.0% 6.8%). be hypertensive (76.35% 41%) dyslipidaemic (58.6% 25.7%) had frequent underlying coronary artery disease (33.6% 12.4%). The rates creatinine levels ≥1.17 mg/L troponin T ≥4 ng/dL higher group non-T2DM (30.4% 15% 93.3% 83.1%, respectively). admitted intensive care unit (ICU) (34.2% 22.1%), require invasive ventilation (18.4% 10.3%) receive vasopressors (16.4% 10.0%). Increasing age use associated odds (odds ratio (OR), 1.08, 9.95 19.83, respectively), whereas longer ICU stay lower (OR, 0.38). 0.27).Among COVID-19, older, presented milder symptoms comorbidities compared T2DM. Despite worse course,