Impact of nutritional status and pulmonary function on short- and long-term overall survival in hemodialysis patients

• DOI: 10.1371/journal.pone.0317510
• Publication Date: 2025-01-27T18:41:15Z
• Authors: Özge Aydın Güçlü; Hasim Atakan Erol; Nilüfer Aylin Ace...; Asli Gorek Dilekt...; Funda Coskun; Abdulmecid Yıldız; Mehmet Karadag
• Keywords: Bioelectrical Impedance Analysis

Background End-stage renal disease (ESRD) patients frequently experience protein-energy wasting (PEW), which increases their morbidity and mortality rates. Objective This study explores the effects of nutritional status pulmonary function on short- long-term ESRD undergoing hemodialysis. Materials methods 67 consecutive maintenance hemodialysis were included in study. The primary outcomes all-cause one-year five-year mortality. Data demographic characteristics, comorbidities, laboratory findings collected. Pulmonary tests conducted along with body composition measurements using bioelectrical impedance analysis (BIA). Malnutrition was assessed Prognostic Nutritional Index (PNI). Results median age 60.9 ± 12.4 years, 58.3% being male. parameters (FEV1 FVC) significantly associated short-term PNI a significant predictor both A score ≤ 39.01 increased (HR: 0.65, 95% CI: 0.48–0.88, p = 0.006), while 40 linked to 0.80, 0.67–0.95, 0.015). Additionally, older 1.06, 1.01–1.12, 0.021) higher glomerular filtration rate (GFR) 1.23, 1.02–1.42, 0.024) related risk. Conclusion demonstrates that PNI, age, are critical factors influencing survival patients. These underscore importance comprehensive assessment improve clinical this population.