NF-YA transcription factors suppress jasmonic acid-mediated antiviral defense and facilitate viral infection in rice

• DOI: 10.1371/journal.ppat.1010548
• Publication Date: 2022-05-13T17:41:46Z
• Authors: Xiaoxiang Tan; Hehong Zhang; Zihang Yang; Zhongyan Wei; Yanjun Li; Jianping Chen; Zongtao Sun
• Keywords: Jasmonic acid; Transcription

NF-Y transcription factors are known to play many diverse roles in the development and physiological responses of plants but little is about their role plant defense. Here, we demonstrate negative rice NF-YA family genes antiviral defense against two different viruses, Rice stripe virus (RSV, Tenuivirus) Southern black-streaked dwarf (SRBSDV, Fijivirus). RSV SRBSDV both induced expression OsNF-YA genes. Overexpression OsNF-YAs enhanced susceptibility infection, while RNAi mutants were more resistant. Transcriptome sequencing showed that jasmonic acid (JA)-related was significantly decreased overexpressing when they infected by viruses. qRT-PCR JA sensitivity assays confirmed regulating pathway. Further experiments physically interact with signaling OsMYC2/3 interfere dissociating OsMYC2/3-OsMED25 complex, which inhibits transcriptional activation activity OsMYC2/3. Together, our results reveal broadly inhibit repressing pathways, provide new insight into how directly associated