Indicators of the need for insulin treatment and the effect of treatment for gestational diabetes on pregnancy outcomes in Japan

• DOI: 10.1507/endocrj.ej15-0427
• Publication Date: 2015-11-24T17:10:22Z
• Authors: Yuzuru Ito; Makoto Shibuya; Saho Hosokawa; Yoko Motoki; Ryou Nagata; Hiromi Konishi; Takashi Miyazaki; Tatsuya Matsunaga; Yoshiyuki Nomura; Takashi Mihara; Shihou Ito; Ken Sugiura; Yasuo Terauchi
• Keywords: Univariate analysis

This study assessed indicators of the need for insulin therapy and effect treatment on pregnancy outcomes in Japanese patients with gestational diabetes mellitus (GDM). All diagnosed GDM were hospitalized three days. Plasma glucose profiles under strict dietary management characteristics high daily levels investigated. Patients who failed to achieve glycemic targets treated insulin. Indicators Pregnancy prescribed compared. The included 112 GDM. hospital exhibited significantly higher 1-h 2-h plasma oral tolerance tests (OGTTs) at diagnosis. In our hospital, 102 singleton pregnancies followed until delivery; 32 (31.3%) Univariate analysis identified significant associations requirement family history OGTT values Multivariate showed that level diagnosis was an independent predictor perinatal outcomes, associated low birth weight.