The relationship between hepatic steatosis and skeletal muscle mass index in men with type 2 diabetes

• DOI: 10.1507/endocrj.ej16-0124
• Publication Date: 2016-07-08T18:05:40Z
• Authors: Yoshitaka Hashimoto; Takafumi Osaka; Takuya Fukuda; Muhei Tanaka; Masahiro Yamazaki; Michiaki Fukui
• Keywords: Steatosis; Transient elastography

Recent cross-sectional studies revealed that sarcopenia is associated with non-alcoholic fatty liver disease (NAFLD) in general population. However, it remains to be elucidated the association between skeletal muscle mass index (SMI) and hepatic steatosis patients type 2 diabetes. In this study of 145 Japanese (79 men 66 women) diabetes, we examined correlation SMI steatosis. Skeletal was estimated from bioimpedance analysis measurements (%) defined as (kg)/total body weight (kg) × 100. Controlled attenuation parameter (CAP) evaluated transient elastography, used for assessment addition, also investigated prevalence NAFLD, which CAP over 237.8 dm-1, using logistic regression analysis. Fifty-eight (74%) thirty-nine (60%) women had NAFLD. Multiple demonstrated independently correlated (β = -0.35, P 0.007) after adjusting age, index, hemoglobin A1c, triglycerides/ HDL-C ratio, C-reactive protein gamma-glutamyl transferase. On other hand, not women. Odds ratio per incremental 1% NAFLD 0.80 (95% CI 0.64-0.97, 0.021) BMI, smoking statues, HbA1c, transferase men. conclusion, negatively