Decreasing Brain Natriuretic Peptide Levels after Treatment for Hyperthyroidism

• DOI: 10.1507/endocrj.k09e-159
• Publication Date: 2009-12-22T06:01:31Z
• Authors: Derun Taner ERTUGRUL; Bunyamin YAVUZ; Naim ATA; Ahmet Arif YALCIN; Metin KUCUKAZMAN; Beyza ALGUL; Kursad DAL; Kadir Okhan AKIN; Onur Sinan DEVECI; Nihat CANBOLAT; Oznur Sari URE; Emre TUTAL
• Keywords: Brain natriuretic peptide; Volume overload

BNP are produced in ventricular cardiomyocytes, and secreted response to volume expansion or pressure overload. The purpose of this study was assess levels patients with hyperthyroidism before specific treatment for after euthyroidism achieved. performed a prospective design. population consisted 48 consecutive newly diagnosed untreated overt hyper-thyroid who had not been treated any anti-thyroid medications before. All subjects underwent transt-horacic echocardiography. Levels fT3, fT4, TSH were measured the onset A significant decrease (102.5 (6.7-1769) ng/L vs. 5.0 (0.1-87.0) p< 0.001) observed, posi-tively correlated fT3 (r=0.298; p=0.049) fT4 (r=0.313; p=0.030). There no cor-relation between (p=NS). We conclude that may cause high measurements which can lead misdiagnosis congestive heart failure. suggest thyroid hormones should be checked BNP.