Clinical Features and Prognosis of Nontuberculous Mycobacterial Pleuritis: A Multicenter Retrospective Study

• DOI: 10.1513/annalsats.202008-938oc
• Publication Date: 2021-04-09T00:31:02Z
• Authors: Kazuma Yagi; Akihiro Ito; Keiji Fujiwara; Eriko Morino; Isano Hase; Yasushi Nakano; Takanori Asakura; Koji Furuuchi; Atsuho Morita; Takahiro Asami; Ho Namkoong; Fumitake Saito; Kozo Morimoto; Makoto Ishii; Yasunori Sato; Hiroki Tateno; Kazumi Nishio; Yoshitaka Oyamada; Koichi Fukunaga; Haruhito Sugiyama; Tadashi Ishida; Atsuyuki Kurashima; Naoki Hasegawa
• Keywords: Pleurisy

Rationale: The clinical features and prognosis of nontuberculous mycobacterial (NTM) pleuritis pleural effusion combined with NTM lung disease remain unclear. Objectives: To investigate the pleuritis. Methods: This retrospective observational study included patients from January 2001 to June 2018 across eight hospitals in Japan. was defined by a positive culture samples. We matched Mycobacterium avium complex (MAC) (MAC-LD) without sex age obtain comparative data investigated association between parameters prognosis. Results: identified 64 (median age, 73 yr; 37 female patients). median follow-up duration 11 months, 27 died. Patients MAC had significantly lower survival rate than MAC-LD Multivariate analysis revealed that (adjusted hazard ratio, 6.99; 95% confidence interval [CI], 2.58-19.00) underlying pulmonary diseases 3.01; CI, 1.44-6.28) were independently associated all-cause mortality MAC-LD. Conclusions: is poorer Pleuritis an independent prognostic factor