Complexity affects regional cerebral blood flow change during sequential finger movements

• DOI: 10.1523/jneurosci.16-08-02691.1996
• Publication Date: 2018-04-05T22:28:20Z
• Authors: N Sadato; G Campbell; V Ibanez; M Deiber; M Hallett
• Keywords: Premotor cortex; Supplementary motor area; Cerebellar vermis; Putamen

Brain regions activated with complex sequential finger movements were localized by measuring regional cerebral blood flow (rCBF) positron emission tomography. Whereas the total number and frequency of kept constant, complexity auditory cued right hand varied, sequence length as independent variable. In four conditions differing complexity, bilateral primary sensorimotor area, left ventral premotor cortex, posterior supplementary motor superior part cerebellum, putamen consistently equally activated. This finding suggests an executive role in running sequences, regardless their length. The dorsal cortex (Brodmann area 6) precuneus 7) showed a linear increase rCBF increased. is consistent hypothesis that these areas function storage sequences spatial working memory production ongoing movement reference to buffered memory. A similar cerebellar vermis thalamus likewise subcortical structures movements. Conversely, inferior parietal lobule decrease Because short-term phonological this we suggest visuospatial system may suppress other systems not use. Our findings recruit discrete set brain areas, addition underlying execution simple sequences.