Functional–Anatomic Correlates of Sustained and Transient Processing Components Engaged during Controlled Retrieval

• DOI: 10.1523/jneurosci.23-24-08460.2003
• Publication Date: 2018-04-12T23:25:04Z
• Authors: Katerina Velanova; Larry L. Jacoby; Mark E. Wheeler; Mark P. McAvoy; Steve E. Petersen; Randy L. Buckner
• Keywords: Functional specialization; Self-reference effect

Controlled processing is central to episodic memory retrieval. In the present study, neural correlates of sustained, as well transient, components were explored during controlled retrieval using a mixed blocked event-related functional magnetic resonance imaging paradigm. Results from 29 participants suggest that certain regions in prefrontal cortex, including anterior left inferior cortex near Brodmann's Area (BA) 45/47 and more posterior dorsal BA 44, increase activity on trial-by-trial basis when high levels control are required Providing direct evidence for processes participate an ongoing basis, right frontal-polar was strongly associated with sustained temporal profile conditions, several additional regions, those within parietal cortex. These results provide dissociation Frontal-polar 10 associate temporally extended may underlie attentional set, or mode, retrieval, whereas individual attempts. particular, involvement reconciles number disparate findings have arisen contrasting blocked-trial paradigms paradigms.